Figure 5

Effect of individual reporters on probe set summaries. A) The expression profiles of the reporters of a probe set A that binds the transcript of a target gene with a sinusoidal expression pattern. Each reporter is drawn in a different color. B) The expression profiles of eleven reporters of a probe set B that show random signals without any underlying trend. Each reporter is drawn in a different color. C) Nine of the reporters of a probe set C have identical expression values as nine of those of probe set B. Two other reporters of this probe set cross-hybridize with the transcript of gene A and thus have a expression pattern that is highly similar to the reporters of probe set A. The expression values of these two reporters are colored red. The other nine have the same colors as the corresponding reporters of probe set B in Figure 5B. D) The expression patterns of these three probe sets after summarization with median polish [15,39,40].