Subcellular location prediction of proteins using support vector machines with alignment of block sequences utilizing amino acid composition

Table 1 Comparison of predictive accuracy for plant proteins in the TargetP data set. "cTP", "mTP", "SP", and "other" indicate proteins destined for chloroplast, mitochondria, secretory pathway, and other locations (nucleus and cytosol), respectively.

Predictor	Location	Sensitivity	Specificity	MCC	Average MCC	Overall Accuracy
Our method	cTP	0.8440	0.9015	0.8507	0.8655	0.9096
	mTP	0.9348	0.9125	0.8735
	SP	0.9665	0.9319	0.9282
	other	0.8148	0.8684	0.8095
Matsuda et al. (2005)	cTP	0.7591	0.8474	0.7694	0.8244	0.8809
	mTP	0.9240	0.8652	0.8227
	SP	0.9219	0.9326	0.8983
	other	0.8210	0.8586	0.8070
Kim et al. (2004)	cTP	0.6874	0.8435	0.7222	0.7791	0.8479
	mTP	0.8970	0.8392	0.7773
	SP	0.8592	0.9428	0.8872
	other	0.8027	0.7549	0.7296
Emanuelsson et al. (2000)	cTP	0.85	0.69	0.72	0.79	0.853
	mTP	0.82	0.90	0.77
	SP	0.91	0.95	0.90
	other	0.85	0.78	0.77

ISSN: 1471-2105