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Table 4 Comparison of predictive accuracy for non-plant proteins in the TargetP data set. "mTP", "SP", and "other" indicate proteins destined for mitochondria, secretory pathway, and other locations (nucleus and cytosol), respectively.

From: Subcellular location prediction of proteins using support vector machines with alignment of block sequences utilizing amino acid composition

Predictor Location Sensitivity Specificity MCC Average MCC Overall Accuracy
Our method mTP 0.7647 0.8990 0.8005 0.8452 0.9204
  SP 0.9157 0.9056 0.8790   
  other 0.9576 0.9324 0.8560   
Matsuda et al. (2005) mTP 0.8303 0.8635 0.8228 0.8542 0.9229
  SP 0.9091 0.9118 0.8788   
  other 0.9498 0.9409 0.8609   
Kim et al. (2004) mTP 0.6483 0.8569 0.7121 0.7635 0.8762
  SP 0.8530 0.8736 0.8158   
  other 0.9389 0.8819 0.7626   
Emanuelsson et al. (2000) mTP 0.89 0.67 0.73 0.8233 0.900
  SP 0.96 0.92 0.92   
  other 0.88 0.97 0.82   
Reczko et al. (2004) mTP 0.78 0.82 0.77 0.8333 0.913
  SP 0.93 0.91 0.89   
  other 0.93 0.94 0.84   
  1. Note: In our method, although gap penalty = 0.4, γ = 2.5, c = 10, w = 20 are given, posconstraint and negconstraint are not specified.