|
Predictor
|
Location
|
Sensitivity
|
Specificity
|
MCC
|
|---|
|
Our method
|
plant mTP
|
0.9348
|
0.8958
|
0.8587
|
|
MitPred (SVM)
|
plant mTP
|
0.8234
|
0.8584
|
0.7418
|
|
MitPred (BLAST+SVM)
|
plant mTP
|
0.9429
|
0.8422
|
0.8158
|
|
MitPred (HMM+SVM)
|
plant mTP
|
0.8668
|
0.8484
|
0.7644
|
|
Our method
|
nonplant mTP
|
0.7547
|
0.8333
|
0.7626
|
|
MitPred (SVM)
|
nonplant mTP
|
0.8194
|
0.8863
|
0.8302
|
|
MitPred (BLAST+SVM)
|
nonplant mTP
|
0.9380
|
0.9355
|
0.9268
|
|
MitPred (HMM+SVM)
|
nonplant mTP
|
0.8571
|
0.9408
|
0.8830
|
- Note: In our methods, parameters shown in Table 2 of the manuscript were used, but "posconstraint" and "negconstraint" were not specified for nonplant mTP. For MitPred, we used default parameters as follows. In SVM method, threshold was set as 0.5. E-value cutoff of BLAST+SVM method was 1e-4. E-value and SVM threshold for HMM based Pfam search+SVM method were 1e-5 and 0.5 respectively.
