Figure 1
From: Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Observational model for three hypothetical trials. Two proteins are connected by an edge if their interaction is tested by a trial. The last row shows the observation from the three trials in their (t, s) values assuming the spoke and matrix model. The spoke model counts pairwise interactions only between bait and preys. The matrix model counts all pairs of proteins in a purification. It follows that the matrix model creates more unsuccessful trials.