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Table 1 Maximum likelihood solution for the spoke model (ψ = 3.5) and the matrix model (ν = 10.0). We choose the number of clusters that maximizes the likelihood by searching over a range of values of K. The estimated the false negative rate is denoted by ν* and the estimated false positive rate by φ*. For comparison we show the error estimates based on the MIPS complexes, ν MIPS and φ MIPS , restricted to proteins with MIPS annotation. See also Table 2.

From: Identifying protein complexes directly from high-throughput TAP data with Markov random fields

Dataset

 

K

ν*

φ*

ν MIPS

φ MIPS

Gavin02

Spoke model

393

0.423

1.3 × 10-3

0.598

6.5 × 10-3

 

Matrix model

310

0.752

1.7 × 10-3

0.717

5.2 × 10-3

Gavin06

Spoke model

698

0.547

2.4 × 10-3

0.637

8.3 × 10-3

 

Matrix model

550

0.807

2.7 × 10-3

0.901

6.4 × 10-3