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Table 1 Network outputs for 25 blind test samples

From: Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clustering

Sample #

EWS

RMS

BL

NB

Actual

1

0.999

0.001

0.000

0.000

Sk. Muscle

2

0.000

0.224

0.000

0.004

Prostate Cancer

3

1.000

0.204

0.000

0.000

Sarcoma

4

0.000

0.000

0.000

1.000

NB

5

0.151

0.157

0.000

0.000

RMS

6

0.039

0.000

0.992

0.000

Sk. Muscle

7

0.016

0.000

0.999

0.000

Osteosarcoma

8

0.000

0.000

0.000

1.000

NB

9

1.000

0.001

0.000

0.008

EWS

10

0.000

1.000

0.000

0.000

RMS

11

0.003

0.000

1.000

0.000

BL

12

1.000

0.000

0.000

0.000

EWS

13

0.000

0.997

0.000

0.000

RMS

14

1.000

0.000

0.000

0.000

EWS

15

1.000

0.001

0.000

0.000

EWS

16

0.309

0.028

0.001

0.000

EWS

17

0.000

1.000

0.000

0.000

RMS

18

0.001

0.000

1.000

0.000

BL

19

0.000

1.000

0.000

0.000

RMS

20

0.000

0.000

0.000

1.000

NB

21

0.000

0.000

0.000

1.000

NB

22

0.000

0.000

0.000

1.000

NB

23

0.000

0.000

0.000

1.000

NB

24

0.000

0.000

1.000

0.000

BL

25

1.000

0.000

0.000

0.000

EWS

  1. The predicted and the actual outputs of a typical run for the 25 blind test samples. These 25 also includes the 5 nonSRBCT cases as marked in column 6 (sample numbers : 1,2,3,6, and 7). All but sample No. 16 of the 25 SRBCT test samples, the support provided by the network for the correct class is almost 1 and for the other classes it is practically 0. For sample No. 16, the support for the correct class is 0.309 but it is about 12 times stronger than the next high output value. Hence, this is also a decision with high confidence. For sample No. 5, although the network classified it correctly, the support for RMS and EWS are 0.157 and 0.151 suggesting further investigation (weak support for the RMS and the next higher support is for EWS, but that is very close to that of RMS.). Due to nonavailability of the patient's identity, this investigation could not be pursued further.