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Table 1 Comparison of existing backtranslation tools.

From: Sequence similarity is more relevant than species specificity in probabilistic backtranslation

 

Training Set

Learning Method

Unsupervised

BBOCUS [10]

Species specific

Clustering and codon frequencies

No

EasyBack

Any

HMM

Yes

BACKTRANSEQ [11]

Species specific

Codon frequencies

Yes

LBT [14]

Any

Alignment and local codon frequencies

Yes

TIP [12]

Any

Genetic algorithm and statistics

Yes