A comparative study of S/MAR prediction tools

BMC Bioinformatics

Table 3 Summary of the MAR-Finder Rules

Rule Number	Purpose of Rule
1	Origin of replication
2	TG-richness
3	Curved DNA
4	Kinked DNA
5	Topoisomerase II cleavage sites
6	AT-richness
7	Consensus motif
8	ATC rule

Each rule is based on a set of motifs thought to be related to a biological feature which itself is likely to be indicative of an S/MAR. In standard use, rules 1–6 are used.

ISSN: 1471-2105