Figure 1

EVDB construction process. Files used for building EVDB are downloaded from "External Data" (see legend at bottom of figure). Downloaded data are converted into EVDB database tables by "Processes". Some tables are processes in themselves ("Process/Table");that is, a process with the same name was implemented to create the table. Small arrowheads on thin lines represent the flow of data. Large arrowheads represent processing within a specific table. Thick lines represent processes other than flow of data. Arrows meeting at one point represent database joins. Bi-directional arrows indicate that a method processes the data in the table and uses the data to create other tables. Algorithms for exon, sub-exon, and splice variant naming are beyond the scope of this paper and will be described elsewhere (Kahn et al., in preparation).