Figure 1

t IDR versus posterior probability of differential expression for the two-study simulation data. True integration-driven discovery rate (t IDR) versus threshold values of posterior probability of differential expression γ ≥ 0.50, for the standardized expression integration model (blue circles) and probability integration model (black diamonds) for the two-study simulation data with high mean ${\tau }_g^2$ = 0.7 (differentially expressed); 0.07 (non-differentially expressed) and the following simulated percent differentially expressed genes p _s : a) 5%; b) 10%; c) 25%.