Orthology prediction at scalable resolution by phylogenetic tree analysis

BMC Bioinformatics

Table 2 Statistics of the LOFT analysis

	COG	FOG
Species	178	27
Genes	294011	126230
*genes per species (average)*	1651.7	4675.2
Orthologous Groups (trees)	4325	8740
*genes per OG (average)*	68.0	14.4
Base groups	21130	11082
Unique spec./base group combinations	227143	103931
*genes in uniq spec./base group comb* .	77%	82%

Statistics of the LOFT analysis of orthologous groups based on COGs and on Fungal Orthologous groups (FOGs). LOFT's parsing of the COGs into high resolution orthologous groups leads to a larger increase in the orthology resolution than the parsing of the FOGs, as reflected in the numbers of base groups. Notably, the FOGs started off with a higher resolution due to the application of the COG methodology on a set of closely related species.

ISSN: 1471-2105