Figure 2
From: Regulation of metabolic networks by small molecule metabolites
An example of a reaction represented first by a bipartite network and second by two monopartite networks. The compounds A and B are substrates of reaction catalysed by EC: 1.2.3.4, C and D are products and E is an inhibitor of EC: 1.2.3.4. In network 2. only the metabolic network is used and substrates are connected to products. In network 3. only the regulatory network is used and the regulator (E) is connected to each of the substrates and products, representing the fact that E regulates the levels of these compounds in some way. Note that E could be one of the products or substrates of the reaction, in which case it is connected to itself.