Figure 6

Counting the number of mutational events. Computing the number of events in 64 × 6144 positions. Each inner node represents the addition of a number of 128 bit words divided into blocks, e.g., 7+ denotes that 7 additions are used to add 8 128-bit words. Along each edge a call to AddBlocks is performed to double the block size. Thus in the nodes with 2+ the block size is 2, in the nodes with 1+ the block size is 4, in the nodes with 7+ the block size is 8, and in 127+ the block size is 16. Finally, another three calls to AddBlocks have to be performed to get all events into one single block.