Figure 2

Conserved residues in the identified 3D match. Graphical view of the conserved residues in the identified 3D match. The ABC transporter (PDB code: 1b0uA) is shown in blue and the HPrK/P (PDB chain code: 1kklA) is in orange. The ploop of the two proteins is represented as a ribbon. The two beta filaments where the catalytic histidine and the hydrophobic residues are encoded in opposite order are also shown as ribbons. The ATP molecule co-crystallized with the histidine transporter subunit is shown colored by atom type; some of the side-chains involved in the functional match are also shown and are identified by their PDB residue number. The two arrows indicate the N to C orientations of the oppositely oriented beta filaments.