Figure 2

Association kinetics for different probability of association and dissociation . The 3D model was used for four different simulations in which the probabilities of association and dissociation were varied as indicated underneath the graphs. In three simulations (violet and cyan triangles and green circles) the ratio between P_on and P_off was kept constant whereas, in the run reported with the red curve, this ratio was varied to observe its impact on the concentration of the different complexes at equilibrium. The lattice sites were seeded with proteins with an occupancy of 20%.