Poorly registered images. Rows correspond to genes Apaf1(0.5387), Reln(0.4720) and Myo5b(0.5148) respectively. About 5% of the registrations were of this quality. First two of these images have large deformation (their medulla is elongated) that couldn't be reconciled with our approach. The third image is rotated and flipped. Our algorithm does not consider this type of transformation for computational reasons (i.e it would blow-up the running time).