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Table 2 Overlapping EC classes, for those cases where there are more than two errors from a true EC class to an assigned EC class.

From: CORRIE: enzyme sequence annotation with confidence estimates

True EC Name of true class Assigned EC Name of assigned class Common activity Difference DNA-directed DNA polymerase DNA-directed RNA polymerase DNA-dependent nucleotidyltransferase Substrate: DNA or RNA NADH dehydrogenase (quinone) NADH dehydrogenase (ubiquinone) NADH dehydrogenase Electron acceptor: quinone or ubiquinone Cellulose 1,4-beta-cellobiosidase Cellulase Hydrolysis of 1,4-beta-D-glucosidic linkages Exo-hydrolysis or endo-hydrolysis Phosphatidylinositol 3-kinase Non-specific Ser/Thr protein kinase Kinase Substrate: PI3 or Ser/Thr NDP-glucose – starch glucosyltransferase Starch synthase Starch glucosyltransferase Substrate: NDP-glucose or ADP-glucose Sodium-transporting two-sector ATPase H+-transporting two-sector ATPase Ion transporting two sector ATPase Ion specificity: NA+ or H+
  1. Column names: True EC/Name – the real EC number/name; Assigned EC/Name – the assigned properties made by CORRIE; Common activity/Difference – similarities and differences of substrate specificity and mechanisms for the corresponding reaction pairs.