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Table 2 Overlapping EC classes, for those cases where there are more than two errors from a true EC class to an assigned EC class.

From: CORRIE: enzyme sequence annotation with confidence estimates

True EC Name of true class Assigned EC Name of assigned class Common activity Difference
2.7.7.7 DNA-directed DNA polymerase 2.7.7.6 DNA-directed RNA polymerase DNA-dependent nucleotidyltransferase Substrate: DNA or RNA
1.6.99.5 NADH dehydrogenase (quinone) 1.6.5.3 NADH dehydrogenase (ubiquinone) NADH dehydrogenase Electron acceptor: quinone or ubiquinone
3.2.1.91 Cellulose 1,4-beta-cellobiosidase 3.2.1.4 Cellulase Hydrolysis of 1,4-beta-D-glucosidic linkages Exo-hydrolysis or endo-hydrolysis
2.7.1.137 Phosphatidylinositol 3-kinase 2.7.11.1 Non-specific Ser/Thr protein kinase Kinase Substrate: PI3 or Ser/Thr
2.4.1.242 NDP-glucose – starch glucosyltransferase 2.4.1.21 Starch synthase Starch glucosyltransferase Substrate: NDP-glucose or ADP-glucose
3.6.3.15 Sodium-transporting two-sector ATPase 3.6.3.14 H+-transporting two-sector ATPase Ion transporting two sector ATPase Ion specificity: NA+ or H+
  1. Column names: True EC/Name – the real EC number/name; Assigned EC/Name – the assigned properties made by CORRIE; Common activity/Difference – similarities and differences of substrate specificity and mechanisms for the corresponding reaction pairs.