Skip to main content

Advertisement

Table 4 Accuracy of AnnoLyze in locating binding sites for small ligands.

From: The AnnoLite and AnnoLyze programs for comparative annotation of protein structures

Ligand Extended name Cases Coverage (%) Average (%) Correct (%) Patcher (%)
ADP ADENOSINE-5'-DISPHOSPATE 172 80.2 93.2 100.0 45.6
AMP ADENOSINE-5'-MONOPHOSPHATE 56 80.4 91.4 100.0 31.0
ANP PHOSPHOAMINOPHOSPHONIC ACID – ADENYLATE ESTER 74 68.9 91.0 100.0 51.3
ATP ADENOSINE-5'-TRIPHOSPHATE 107 72.9 92.7 97.4 57.7
BOG B-OCTYLGLUCOSIDE 31 54.8 71.9 76.5 18.2
CIT CITRIC ACID 52 61.5 82.2 90.6 33.3
FAD FLAVIN-ADENINE DINUCLEOTIDE 110 91.8 96.1 100.0 60.9
FMN FLAVIN MONONUCLEOTIDE 62 85.5 94.5 100.0 60.0
FUC FUCOSE 35 82.9 67.9 72.4 0.0
GAL D-GALACTOSE 70 80.0 84.5 92.9 41.7
GDP GUANOSINE-5'-DIPHOSPHATE 72 95.8 93.2 97.1 33.3
GLC GLUCOSE 115 80.0 84.1 93.5 35.3
HEC HEMEC 42 95.2 96.9 100.0 55.6
HEM PROTOPRPHYRIN IX CONTAINING FE 360 94.7 97.1 99.7 73.4
MAN ALPHA D-MANNOSE 52 86.5 84.6 95.6 15.4
MES ETHANESULFONIC ACID 53 43.4 78.2 82.6 29.4
NAD NICOTAMINE ADENINE DINUCLEOTIDE 183 85.8 95.9 100.0 55.6
NAG N-ACETYL-D-GLUCOSAMINE 153 86.9 84.8 94.7 4.6
NAP NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 73 84.9 93.6 98.4 65.4
NDP NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 64 85.9 94.9 100.0 58.3
Average   97 79.9 88.4 94.6 41.3
  1. The last column shows the percentage of correct predictions by the Patcher algorithm.