Bayesian model for regulatory DNA and score function. (a) Energy count histogram Wdat(E) for CRP sites in E. coli as in fig. 3 (log scale), model distribution W(E) (thick line), and its decomposition (25) into background component (1 - λ)P0(E) (thin dashed line) and component λ Q(E) (E <E
≈ 13) of functional sites (thin solid line). (b) Log-likelihood score S(E) = log [Q(E)/P0(E)] (shifted by a constant, thick line) and probability of functionality ρ
(E) (thin line). From .