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Figure 9 | BMC Bioinformatics

Figure 9

From: Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription factor binding, retroviral DNA terminus dynamics, and retroviral integrase-DNA binding

Figure 9

Top: the mfold secondary structure map of the Y-aptamer used in the integrase binding study. Integrase will bind to the blunt-ended arm shown in the yellow circle, where the HIV DNA Terminus consensus sequence has been place. Bottom: Blockade signals produced before (left) and after (right) introduction and possible binding of HIV Integrase to the HIV-corresponding terminus of one arm of a channel-captured y-shaped aptamer. The time elapsed during each frame is approximately three seconds.

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