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Figure 6 | BMC Bioinformatics

Figure 6

From: Computational analysis of biological functions and pathways collectively targeted by co-expressed microRNAs in cancer

Figure 6

Comparison of 12 pathways known to be affected in colon cancer and targeted by miRNAs that are over-expressed in colon cancer. Color of the bars represents 4 data sets. Detailed description could be found in the Results section. A. Ratio of affected genes to total number of genes in the pathway. Reference gene set and three target sets are included: a complete list (all targets) and two sets trimmed by excluding genes from GO categories targeted by less than 50% or less than 100% of miRNAs in the group. B. Significance of enrichment. Threshold p < 0.05 is shown as yellow line. Bars that are above the line indicate significant enrichment of a pathway.

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