|
AKT3
|
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
|
Cytoplasm
|
kinase
|
enzastaurin
|
|
APC
|
adenomatosis polyposis coli
|
Nucleus
|
enzyme
| |
|
BAX
|
BCL2-associated X protein
|
Cytoplasm
|
other
| |
|
BCL2L11
|
BCL2-like 11 (apoptosis facilitator)
|
Cytoplasm
|
other
| |
|
BIRC5
|
baculoviral IAP repeat-containing 5 (survivin)
|
Cytoplasm
|
other
| |
|
BRCA1
|
breast cancer 1, early onset
|
Nucleus
|
transcription regulator
| |
|
CCND1
|
cyclin D1
|
Nucleus
|
other
| |
|
DIABLO
|
diablo homolog (Drosophila)
|
Cytoplasm
|
other
| |
|
EP300
|
E1A binding protein p300
|
Nucleus
|
transcription regulator
| |
|
ERBB3
|
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
|
Plasma Membrane
|
kinase
| |
|
FASLG
|
Fas ligand (TNF superfamily, member 6)
|
Extracellular Space
|
cytokine
| |
|
FLT1
|
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
|
Plasma Membrane
|
kinase
|
sunitinib, axitinib
|
|
FST
|
follistatin
|
Extracellular Space
|
other
| |
|
GSK3A
|
glycogen synthase kinase 3 alpha
|
Nucleus
|
kinase
| |
|
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
|
Plasma Membrane
|
transmembrane receptor
| |
|
MAP2K1
|
mitogen-activated protein kinase kinase 1
|
Cytoplasm
|
kinase
|
PD 0325901
|
|
MAPK9
|
mitogen-activated protein kinase 9
|
Cytoplasm
|
kinase
| |
|
MAPK14
|
mitogen-activated protein kinase 14
|
Cytoplasm
|
kinase
|
SCIO-469
|
|
NFAT5
|
nuclear factor of activated T-cells 5, tonicity-responsive
|
Nucleus
|
transcription regulator
| |
|
NUAK1
|
NUAK family, SNF1-like kinase, 1
|
Unknown
|
kinase
| |
|
PARP1
|
poly (ADP-ribose) polymerase family, member 1
|
Nucleus
|
enzyme
|
INO-1001
|
|
PDCD4
|
programmed cell death 4 (neoplastic transformation inhibitor)
|
Nucleus
|
other
| |
|
PLK1
|
polo-like kinase 1 (Drosophila)
|
Nucleus
|
kinase
| |
|
PPP2R1B
|
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
|
Unknown
|
phosphatase
| |
|
PRKCA
|
protein kinase C, alpha
|
Cytoplasm
|
kinase
|
safingol
|
|
PRKG1
|
protein kinase, cGMP-dependent, type I
|
Cytoplasm
|
kinase
| |
|
SRC
|
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
|
Cytoplasm
|
kinase
|
dasatinib
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
Plasma Membrane
|
kinase
| |
|
YES1
|
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
|
Cytoplasm
|
kinase
|
dasatinib
|
