Table 2 Description of features selected for the classifiers built for the two datasets.

Number of prolines

Percent glycine

Percent alanine

Percent leucine

Percent polar amino acids

Percent hydrophobic amino acids

Percent positive amino acids

Percent negative

Size (Dawson, 1972)

Optimized transfer energy parameter (Oobatake et al., 1985)

Weights for beta-sheet at the window position of 5 (Qian-Sejnowski, 1988)

Transfer free energy from oct to wat (Radzicka-Wolfenden, 1988)

Information measure for C-terminal turn (Robson-Suzuki, 1976)

Amphiphilicity index (Mitaku et al., 2002)

Number of cytosienes

Signal sequence helical potential (Argos et al., 1982)

Transer free energy to surface (Bull-Breese, 1974)

Normalized relative frequency of alpha-helix (Isogai et al., 1980)

Normalized relative frequence of double bend (Isogai et al., 1980)

Distance between C-alpha and centroid fo side chain (Levitt, 1976)

Retention coefficient in NAH2PO4 (Meek-Rossetti, 1981)

Interior composition of amino acids intracellular proteins (Fukuchi-Nishikawa, 2001)

Linker propensity from 1-linker dataset (George-Heringa, 2003)