Figure 11From: The α-Hemolysin nanopore transduction detector – single-molecule binding studies and immunological screening of antibodies and aptamersY-aptamer, with TATA Box, that binds TBP. Red curve: Profile of Y-aptamer signal blockades before introduction of TBP. Blue curve: Y-aptamer signal blockade after introduction of TBP. A drastically different signal profile, possibly indicative of significant conformational change in the Y-aptamer upon TBP binding.Back to article page