Examples of reconstructed profiles for two representative genes from the interwoven design. For the gene-specific methods (based on log-ratios estimate) the ratios are expressed relative to T1 and the ratio T1/T1 is set to zero. For the two-stage (ANOVA) methods, the estimated VG effect (gene-variety) is plotted. (a) Estimated profiles for the Ribosomal like gene under the interwoven design. (b) Reconstructed time profile for the gene MGC85244 under the interwoven design.