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Table 6 Distribution of tryptic peptide fragments of colligin-2 among the tissue sections of different groups Peptide masses obtained by MALDI-FTICR MS are listed that match within 2 ppm with the calculated values of enzymatic by trypsin digested fragments.

From: A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation

SwissProt™ accession code P50454, name: Collagen-binding protein 2 precursor (Colligin 2)

Measured mass MH+ (Da)

Calculated mass MH+ (Da)

ppm

p-value Intensity H against S

Intensity H > S

Glioma vessels (H)

Normal vessels (S)

Glioma tissue (TH)

Normal tissue (TS)

1021.5304 #

1021.53213

1.69

0.77475

no

1

2

0

3

1293.6805

1293.67973

0.60

0.01244

yes

5

1

1

3

1659.8011 *

1659.80126

0.10

0.02170

yes

5

1&

0

0

1675.7747 ?

1675.77577

0.64

0.01088

yes

1

0

2

4

  1. * WARP-LC MS-MS MALDI-TOF glioma tissue and vessels (see additional file 1)
  2. # SwissProt™ accession code: P07196, name: Neurofilament triplet L protein, identified by WARP-LC MS-MS MALDI-TOF on normal tissue and vessels (see additional file 1)
  3. ? SwissProt™ accession code: P17677, name: Neuromodulin (Axonal membrane protein GAP-43) ?
  4. &outlier sample S10