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Table 7 Wilcoxon-Mann-Whitney p-values of Myosin-9 peptide peak mass intensities between the "glioma vessels" (series H) and "normal vessels" (series S) The p-value gradually drops from 0.60387 to 0.00310 from start position 711 to 1923 of the amino acid in the protein.

From: A software application for comparing large numbers of high resolution MALDI-FTICR MS spectra demonstrated by searching candidate biomarkers for glioma blood vessel formation

MS-MS

Position start

Position end

Observed mass MH+

Calculated mass MH+

ppm

Missed cleavages

Sequence

Wilcoxon-Mann-Whitney p-value

Mean intensity glioma vessels (H) *103 (A.U.)

Mean intensity normal vessels (S) *103 (A.U.)

Intensity H/S

 

711

717

924.4946

924.49373

0.94

0

R.VVFQEFR.Q

0.60387

117

30

4

*

745

754

1193.6166

1193.61604

0.47

0

K.ALELDSNLYR.I

0.75200

100

44

2

 

1277

1294

1946.0059

1946.00763

0.89

0

K.LQVELDNVTGLLSQSDSK.S

0.33559

287

179

2

*

1301

1321

2493.174

2493.17392

0.03

0

K.DFSALESQLQDTQELLQEENR.Q

0.04085

211

45

5

 

1417

1432

1949.9955

1949.99268

1.45

0

R.LQQELDDLLVDLDHQR.Q

0.01285

264

95

3

 

1730

1750

2472.1699

2472.17356

1.48

0

R.IAQLEEELEEEQGNTELINDR.L

0.05363

154

11

14

*

1754

1769

1869.9677

1869.96645

0.67

0

K.ANLQIDQINTDLNLER.S

0.00170

263

39

7

 

1923

1932

1155.6643

1155.66325

0.91

1

R.GDLPFVVPRR.M

0.00310

82

7

11

  1. * WARP-LC MS-MS MALDI-TOF glioma tissue and vessels (see additional file 1)