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Figure 2 | BMC Bioinformatics

Figure 2

From: Normalization of oligonucleotide arrays based on the least-variant set of genes

Figure 2

Plot of the t-statistic versus the log standard-error. Plot of the t-statistic versus the log standard-error for MAS5 expression values of the Golden-Spike data normalized using different methods. All normalization were performed after summarization of probe intensities. The FC1-based normalizations are ideal, and in real non-spike-in studies are not possible. LVS-normalization is closet to the FC1-based normalization. The others show negative bias for FC1 genes and suppressed values for genes with FC≥ 2.

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