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Table 1 Absolute and relative (in parentheses) concordances between different normalization algorithms applied to MAS5 expression values. The numbers of genes declared DE are determined using the local false discovery rate [8] at 0.1% limit. Percentages in parenthesis are relative to the method in the column headings. The last line reports the percentages of over-expressed genes among those declared DE.

From: Normalization of oligonucleotide arrays based on the least-variant set of genes

 

Global

Invariantset

Quantile

Loess

Global

132

110 (0.82)

93 (0.96)

100 (0.96)

Invariantset

110 (0.83)

134

97 (1.00)

103 (0.99)

Quantile

93 (0.70)

97 (0.72)

97

92 (0.88)

Loess

100 (0.76)

103 (0.77)

92 (0.95)

104

% over-expressed

0.88

0.93

0.9

0.93