Figure 3From: Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein designBinding affinities. Calculated and experimental differences in binding affinity upon mutation for 6 different protein-ligand systems: Aspartyl- and Tyrosyl-tRNA synthetases (AspRS+TyrRS), a Lysozyme-antibody complex (Lyso), the CD4 complex with the gp120 component (CD4), and the BPTI complexes with trypsin and chymotrypsin.Back to article page