Comparison of poly(A) prediction sensitivities for chosen PSSMs using different scanning approaches. The mean sensitivities after 15 runs of tenfold cross-validation are presented for whole intergenic region scanning and for 3 limited scanning ranges (from the putative splice-junction to 500, 1000, and 1500 positions upstream. (A) Mean sensitivities using a PSSM size of 25A25 (25 bases upstream and downstream of the mapped poly(A) position). (B) Mean sensitivities using a PSSM size of 75A600. (C) Mean sensitivities using a combination of both PSSMs (see Results for details).