Skip to main content

Table 1 Prediction in biological assessment. Summary of the light and heavy chain and sex prediction obtained for 47 new patients.

From: A new method for class prediction based on signed-rank algorithms applied to Affymetrix® microarray experiments

Patient Sex Light chain Heavy chain
  NS errors PAM score File NS errors PAM score File NS errors PAM score File
  F M P F M P   κ λ P κ λ P   A G P A G P  
E4006 11 0 M 0.000 1.000 M M 9 3 λ 0.000 1.000 λ λ 9 1 G 1.000 0.000 A A
E4020 0 10 F 0.168 0.832 M F 11 1 λ 0.000 1.000 λ λ 23 0 G 0.000 1.000 G G
E4038 0 10 F 1.000 0.000 F F 0 64 κ 1.000 0.000 κ κ Light chain myeloma
E4049 0 10 F 0.000 1.000 M F 0 52 κ 1.000 0.000 κ κ Light chain myeloma
E4050 11 10 MY- 0.000 1.000 MY- MY- 1 50 κ 1.000 0.000 κ κ 15 0 G 0.000 1.000 G G
E4054 11 0 M 0.000 1.000 M M 0 48 κ 0.903 0.097 κ κ 41* 61* A 0.077 0.923 G A
E4055 11 0 M 0.000 1.000 M M 23 0 λ 0.000 1.000 λ λ 56 1 G 0.000 1.000 G G
E4056 0 10 F 1.000 0.000 F F 0 55 κ 1.000 0.000 κ κ 1 2 A 1.000 0.000 A A
E4057 11 0 M 0.000 1.000 M M 7 3 λ 0.008 0.992 λ λ 29 0 G 0.995 0.005 A G
E4060 11 0 M 0.000 1.000 M M 0 35 κ 1.000 0.000 κ κ 48 0 G 0.000 1.000 G G
E4067 11 0 M 0.000 1.000 M M 0 50 κ 1.000 0.000 κ κ 57 0 G 0.000 1.000 G G
E4071 11 0 M 0.000 1.000 M M 0 51 κ 1.000 0.000 κ κ 59 0 G 0.000 1.000 G G
E4073 0 10 MY- 0.000 1.000 MY- MY- 0 58 κ 1.000 0.000 κ κ 48 0 G 0.000 1.000 G G
E4078 0 10 F 0.000 1.000 M F 8 1 λ 0.000 1.000 λ λ IgD myeloma
E4085 0 10 F 0.001 0.999 M F 15 2 λ 0.003 0.997 λ λ Light chain myeloma
E4094 11 0 M 0.000 1.000 M M 0 51 κ 0.770 0.230 κ κ 0 17 A 0.254 0.746 G A
E4105 0 10 F 0.000 1.000 M F 6 3 λ 0.000 1.000 λ λ Light chain myeloma
E4106 0 10 F 0.996 0.004 F F 0 42 κ 0.997 0.003 κ κ 0 5 A 0.065 0.935 G A
E4121 0 10 F 0.000 1.000 M F 27 0 λ 0.000 1.000 λ λ 27 0 G 0.000 1.000 G G
E4122 11 10 MY- 0.000 1.000 MY- MY- 0 59 κ 0.999 0.001 κ κ 0 16 A 1.000 0.000 A A
E4126 11 0 M 0.000 1.000 M M 0 50 κ 0.983 0.017 κ κ 0 17 A 1.000 0.000 A A
E5007 0 10 F 0.000 1.000 M F 0 32 κ 1.000 0.000 κ κ 2 3 A 0.291 0.709 G A
E5024 11 0 M 0.000 1.000 M M 0 51 κ 0.999 0.001 κ κ IgD myeloma
E5029 0 10 F 0.000 1.000 M F 28 0 λ 0.000 1.000 λ λ Light chain myeloma
E5035 0 10 F 1.000 0.000 F F 0 56 κ 0.994 0.006 κ κ 52 0 G 0.000 1.000 G G
E5038 11 10 MY- 0.000 1.000 MY- MY- 0 59 κ 0.974 0.026 κ κ Light chain myeloma
E5040 0 10 F 0.001 0.999 M F 1 38 κ 0.998 0.002 κ κ 96* 43* G 0.000 1.000 G G
E5043 0 10 F 0.001 0.999 M F 0 48 κ 0.994 0.006 κ κ 45 0 G 0.000 1.000 G G
E5046 0 10 F 0.000 1.000 M F 28 0 λ 0.000 1.000 λ λ 0 19 A 1.000 0.000 A A
E5048 11 0 M 0.000 1.000 M M 25 0 λ 0.000 1.000 λ λ 17 0 G 0.000 1.000 G G
E5049 0 10 F 0.001 0.999 M F 1 48 κ 0.996 0.004 κ κ 52 0 G 0.000 1.000 G G
E5065 11 0 M 0.000 1.000 M M 25 0 λ 0.001 0.999 λ λ Light chain myeloma
E5066 0 10 F 0.000 1.000 M F 28 0 λ 0.008 0.992 λ λ Light chain myeloma
E5068 0 10 F 0.000 1.000 M F 16 0 λ 0.122 0.878 λ λ 0 17 A 0.875 0.125 A A
E5069 0 10 F 0.001 0.999 M F 0 62 κ 0.695 0.305 κ κ 104* 44* G 0.000 1.000 G G
E5081 0 10 F 0.000 1.000 M F 26 0 λ 0.212 0.788 λ λ 33 0 G 0.000 1.000 G G
E5084 11 10 MY- 0.000 1.000 MY- MY- 23 0 λ 0.088 0.912 λ λ 0 18 A 0.019 0.981 G A
E5087 0 10 F 1.000 0.000 F F 0 61 κ 0.912 0.088 κ κ 55 0 G 0.000 1.000 G G
E5093 0 10 F 0.999 0.001 F F 1 35 κ 0.978 0.022 κ κ 43 0 G 0.000 1.000 G G
E5103 0 10 F 1.000 0.000 F F 1 39 κ 0.997 0.003 κ κ 47 0 G 0.000 1.000 G G
E5104 11 0 M 0.000 1.000 M M 0 51 κ 0.927 0.073 κ κ Light chain myeloma
E5106 0 10 F 0.002 0.998 M F 0 58 κ 0.873 0.127 κ κ 0 7 A 0.552 0.448 A A
E5125 11 0 M 0.000 1.000 M M 3 13 κ 0.841 0.159 κ κ 5 1 G 0.000 1.000 G G
E5126 11 10 MY- 0.000 1.000 MY- MY- 0 38 κ 0.236 0.764 λ κ 9 0 G 0.000 1.000 G G
E5136 0 10 F 1.000 0.000 F F 0 59 κ 0.391 0.609 λ κ Light chain myeloma
E5138 11 0 M 0.000 1.000 M M 17 1 λ 0.000 1.000 λ λ Light chain myeloma
E5139 0 10 F 0.003 0.997 M F 11 1 λ 0.000 1.000 λ λ 21 0 G 0.000 1.000 G G
E6002 11 0 M 0.000 1.000 M M 0 46 κ 0.958 0.042 κ κ Light chain myeloma
E6003 11 0 M 0.000 1.000 M M 0 53 κ 0.975 0.025 κ κ 44* 65* A 0.855 0.145 A A
E6008 11 0 M 0.000 1.000 M M 0 26 κ 0.891 0.109 κ κ 29 1 G 0.000 1.000 G G
E6011 11 0 M 0.000 1.000 M M 0 56 κ 0.975 0.025 κ κ 49 0 G 0.000 1.000 G G
E6020 11 10 MY- 0.000 1.000 M F 16 0 λ 0.000 1.000 λ λ 6 0 G 0.000 1.000 G G
E6022 0 10 F 1.000 0.000 F F 0 39 κ 1.000 0.000 κ κ 0 4 A 1.000 0.000 A A
E6024 11 0 M 0.000 1.000 M M 10 1 λ 0.000 1.000 λ λ IgD myeloma
E6025 11 0 M 0.000 1.000 M M 4 13 κ 0.003 0.997 λ κ 30 1 G 1.000 0.000 A G
E6026 0 10 F 0.001 0.999 M F 0 27 κ 1.000 0.000 κ κ 36 0 G 0.000 1.000 G G
E6049 11 0 M 0.000 1.000 M M 0 12 κ 1.000 0.000 κ κ 2 4 A 0.008 0.992 G A
E6054 11 0 M 0.000 1.000 M M 0 40 κ 1.000 0.000 κ κ 3 8 A 0.002 0.998 G A
E6056 11 0 M 0.000 1.000 M M 0 37 κ 1.000 0.000 κ κ 0 6 A 1.000 0.000 A A
E6063 11 10 MY- 0.000 1.000 MY- MY- 1 13 κ 0.999 0.001 κ κ 8 1 G 0.000 1.000 G G
E6074 11 0 M 0.000 1.000 M M 0 22 κ 1.000 0.000 κ κ Light chain myeloma
E6077 11 0 M 0.000 1.000 M M 1 31 κ 1.000 0.000 κ κ 51 0 G 0.000 1.000 G G
E6087 0 10 F 0.002 0.998 M F 15 1 λ 0.000 1.000 λ λ 0 8 A 1.000 0.000 A A
E6092 0 10 F 1.000 0.000 F F 17 1 λ 0.000 1.000 λ λ 67* 50* G 0.000 1.000 G G
E6100 0 10 F 1.000 0.000 F F 1 25 κ 0.477 0.523 λ κ 70* 44* G 0.000 1.000 G G
E6108 0 10 F 1.000 0.000 F F 0 46 κ 1.000 0.000 κ κ Light chain myeloma
E6117 0 10 F 0.009 0.991 M F 13 1 λ 0.001 0.999 λ λ Light chain myeloma
E6120 11 0 M 0.000 1.000 M M 16 2 λ 0.000 1.000 λ λ 0 2 A 1.000 0.000 A A
  1. Abbreviations:
  2. F: female, M: male
  3. P: predicted
  4. MY-: male with Y chromosome deletion
  5. A: IgA, G: IgG
  6. *: When the number of non significant comparisons is identical in both classes for the call predictor at a given precision of the Bonferroni-corrected χ2 sample-to-sample comparisons, the P-value is increased by one log unit, adding intra-class errors to interclass ones, but still leading to a correct classification.