Figure 3

Comparison of the Positive Predictive Values for several methods relative to the corresponding random performance. The methods are grouped according to the domain definition. Note that performance of Random varies between the groups. GPE* denotes results obtained by projecting supra-domain from the GPE method is back into Pfam domains where the "children" domains inherit the scores from the supra-domain. A more formal comparison method from different groups and relies on counting how often each of them over/under-performed the corresponding random selection and is described in the text. The performance of GPE and PE was identical while their desistance to the next closed method was statistically significant.