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Table 2 Cancer gene enrichment of proteins according to the number of cancer types in which they appear differentially expressed. The enrichment of cancer genes is shown for proteins differentially expressed in 1, 2 and 5 cancer types. The p-value of the difference between the different groups of proteins was calculated using the Fisher's exact test for count data (F) and the Wilcoxon signed rank test (W) on 1000 random samples.

From: Predicting cancer involvement of genes from heterogeneous data

 

All in dataset

1 cancer type

2 cancer types

5 cancer types

% of cancer genes

4%

8%

11%

22%

  

p-values

p-values

p-values

  

all vs. 1 < 2.2 × 10-16 (W)

all vs. 2 < 2.2 × 10-16 (W)

all vs. 5 < 2.2 × 10-16 (W)

   

1 vs. 2 = 2.6 × 10-11 (F)

1 vs. 2 = 2.6 × 10-11 (F)

    

2 vs. 5 = 2.0 × 10-13 (F)