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Figure 1 | BMC Bioinformatics

Figure 1

From: Local conservation scores without a priori assumptions on neutral substitution rates

Figure 1

Comparison of scores. Comparison of KuLCons score signal to the phastCons, GERP and SCONE scores over an ENCODE region (hg17, ENm005, chr21:32677595-32677794). Scores have been smoothed using a Gauss window with σ w = 0.2 with size 15 (δ = 7). In order to facilitate comparison we plot the transformed version 1 σ i max i { σ i } MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaeGymaeJaeyOeI0scfa4aaSaaaeaacqaHdpWCdaWgaaqaaiabdMgaPbqabaaabaGagiyBa0MaeiyyaeMaeiiEaG3aaSbaaeaacqWGPbqAaeqaaiabcUha7jabeo8aZnaaBaaabaGaemyAaKgabeaacqGG9bqFaaaaaa@3D70@ of our score and applied a similar transformation to the GERP scores in order to have scores in therange [0, 1]. In the alignment, bases with darker background represent bases identical to consensus.

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