Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles

BMC Bioinformatics

Table 2 The performance of SVM models developed using amino acid and PSSM matrix composition.

Thr	Split Amino acids composition				PSSM Matrix composition
	Sn*	Sp	Acc	MCC	Sn	Sp	Acc	MCC
-1.0	93.25	43.55	68.60	0.42	97.22	44.84	71.03	0.49
-0.9	93.25	50.00	71.80	0.48	95.63	58.73	77.18	0.58
-0.8	92.46	56.05	74.40	0.52	95.24	65.08	80.16	0.63
-0.7	91.27	59.68	75.60	0.54	94.05	70.24	82.14	0.66
-0.6	90.48	62.10	76.40	0.55	94.05	75.00	84.52	0.70
-0.5	87.70	64.11	76.00	0.53	92.86	84.13	88.49	0.77
-0.4	85.71	70.16	78.00	0.57	91.27	90.08	90.67	0.81
-0.3	84.92	73.39	79.20	0.59	90.08	91.27	90.67	0.81
-0.2	83.73	78.63	81.20	0.62	90.08	92.86	91.47	0.83
-0.1	83.33	82.26	82.80	0.66	89.29	94.05	91.67	0.83
0.0	81.75	87.50	84.60	0.69	89.29	94.84	92.06	0.84
*0.1*	*79.37*	*93.55*	*86.40*	*0.74*	88.89	95.24	92.06	0.84
0.2	77.38	94.76	86.00	0.73	*88.49*	*96.83*	*92.66*	*0.86*
0.3	76.19	96.37	86.20	0.74	87.30	97.22	92.26	0.85
0.4	73.81	97.98	85.80	0.74	85.71	97.22	91.47	0.83
0.5	71.43	97.98	84.60	0.72	85.32	98.41	91.87	0.84
0.6	69.84	97.98	83.80	0.71	84.92	98.81	91.87	0.85
0.7	68.25	97.98	83.00	0.69	83.73	98.81	91.27	0.83
0.8	65.87	97.98	81.80	0.67	82.94	99.21	91.07	0.83
0.9	63.10	98.39	80.60	0.66	80.16	99.21	89.68	0.81
1.0	58.73	99.60	79.00	0.64	73.41	100.00	86.71	0.76

*Sn: Sensitivity; Sp: Specificity; Acc: Accuracy; MCC: Mathews Correlation Coefficient

ISSN: 1471-2105