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Table 1 Pairwise species comparisons for co-expression-based disease gene ranking.

From: Conserved co-expression for candidate disease gene prioritization

Individual species # Disease gene pairs Median rank Pairwise combined sets # Disease gene pairs Median rank P-value (Combined better than single species)
Human 3286 0.64 Human-Mouse 3114 0.67 6.7 × 10-4 *
Mouse 3188 0.63     1.3 × 10-5 *
Human 3286 0.64 Human-Fly 3176 0.66 0.007 *
Fly 3534 0.62     1.8 × 10-5 *
Human 3286 0.64 Human-Worm 2954 0.67 2.1 × 10-4 *
Worm 3264 0.63     9.1 × 10-6 *
Human 3286 0.64 Human-Yeast 550 0.67 0.12
Yeast 674 0.69     0.74
  1. * statistically significant at p = 0.05 level