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Table 1 Benchmark Times for the Proposed Procedure.

From: An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptimal folding solutions

A. Generated test cases

dist1

dist2

n

e

numMuts

Time (sec)

5

5

20

8

1

1

5

5

20

8

2

5

5

5

20

8

3

21

5

5

20

8

4

63

5

5

20

8

5

124

10

10

40

8

1

3

10

10

40

8

2

14

10

10

40

8

3

64

10

10

40

8

4

341

10

10

40

8

5

1448

15

15

60

8

5

23469

10

10

40

7

2

11

10

10

40

8

2

14

10

10

40

9

2

25

10

10

40

10

2

43

10

10

40

12

2

103

10

10

40

14

2

328

5

5

20

8

2

5

10

10

40

8

2

14

15

15

60

8

2

35

20

20

80

8

2

135

30

30

120

8

2

163

5

5

20

8

3

21

10

10

40

8

3

64

15

15

60

8

3

266

20

20

80

8

3

512

25

25

100

8

3

1032

30

30

120

8

3

1827

40

40

160

8

3

5176

B. Examples reported in the Results Section:

dist1

dist2

n

e

numMuts

Time (sec)

4

4

23

15

2

23

25

25

93

15

3

437

15

15

64

15

2

172

12

12

45

12

2

158

  1. Benchmark times for some generated test cases and for the examples reported in the Results Section, performed on a stand-alone PC with a 2.8 GHz Intel dual-core processor. Highlighted are the parameter values that were varied each time.