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Figure 3 | BMC Bioinformatics

Figure 3

From: Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites

Figure 3

Classification tree for identification of mRNAs with alternative translation initiation sites (aTIS). The C4.5 classification are displayed here in the form of a decision tree. Training, testing, and cross-validation produced a set of 'if-then' rules that allowed the sequences containing the aTISs to be classified independently from sequences that do not possess aTISs. The critical parameters for the classification tree consisted of number of upstream AUGs, 5'-UTR length, consensus sequences (at positions-6/-7), the presence or absence of the Internal Ribosome Entry Site (IRES) structure, as well as G/C ratio.

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