Table 1 Relative importance of interface properties to the Random Forest accuracy for discriminating specific and non-specific protein-protein interfaces.

interface area

1.0

number of intermolecular hydrogen bonds

0.553

210 contacting residues pair counts*

0.224

20 residue propensities*

0.184

evolutionary conservation

0.168

leucine residue propensity

0.104

phenylalanine residue propensity

0.0950

symmetric/non-symmetric interface

0.0896

isoleucine residue propensity

0.0753

packing density

0.0665

tyrosine residue propensity

0.0619

number of leucine-valine contacts

0.0570

Number of leucine-glutamine contacts

0.0500