Top impact flux knock-outs. Impact of the 20 fluxes which have a larger impact on the volume of the space of solution. Here S
= S0 - S
( = 0)measures the difference of the volume of the unperturbed system and that modified by setting = 0. In the x-axis we indicate the relative flux name using upper-case keys for internal fluxes, and lower-case to exchange fluxes.