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Figure 1 | BMC Bioinformatics

Figure 1

From: A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model

Figure 1

Connections between molecular targets, pathways, cellular processes and endpoints. This is illustrated for 5 molecular targets (nuclear DNA, and the nuclear receptors CAR, PXR, AHR and PPARα), three molecular pathways, and three cellular phenotypes, with liver tumors being the final endpoint. The connections have differing strengths or probabilities and are modulated by the collection of interactions of a given chemical with the molecular targets.

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