Figure 1

Genome-wide distribution of linkages from single trait analyses. The yeast genome was divided into non-overlapping 20 kb bins and the number of significant linkages to that bin was recorded. In total, 5013 gene expression traits showed significant linkage (FDR = 0.05) in the single trait analyses. The probability of any bin having 20 linkages or more by chance is less than 2.1E-4. This is denoted by the solid red line (Methods). Details about each linkage hotspot are summarized in Table 1.