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Table 1 Summary of single trait linkage analyses

From: Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis

Group Bin: Chromosome, Coordinate N X/T P-adj Common GO Annotation
1 I: 52357 23 10/215 < 0.001 lipid/fatty acid metabolism
2 II: 368991 74 NA NA NA
3 II: 554641 514 80/213 < 0.001 ribosome biogenesis
4 II: 667104 99 22/213 < 0.001 cytoplasm organization and ribosome bio-genesis, rRNA processing
5 III: 90986 265 49/99 < 0.001 amino acid biosynthesis
6 III: 201166 53 5/8 < 0.001 regulation of transcription, mating-type specific
7 V: 116389 40 3/13 < 0.001 pyrimidine base biosynthesis
8 V: 422588 287 44/171 < 0.001 cytosolic ribosome
9 VII: 55461 42 10/252 0.001 cytoplasm organization and ribosome bio-genesis
10 VIII: 111679 153 18/100 < 0.001 conjugation, response to pheromone
11 X: 329085 21 NA NA NA
12 XII: 671271 182 24/45 < 0.001 ergosterol/sterol metabolism
13 XII: 1051813 44 15/84 < 0.001 helicase activity, telomerase maintenance
14 XIII: 49969 65 3/5 0.008 serine family amino acid metabolism
15 XIV: 486861 511 61/83 < 0.001 mitochondrial ribosome
16 XV: 172654 458 37/218 < 0.001 carbohydrate metabolism
17 XV: 563943 38 18/46 < 0.001 oxidative phosphorylation/respiratory- chain phosphorylation
  1. eQTL positions of the 5013 traits for which linkage was detected at an FDR cutoff of 0.05, were binned into 20 kb bins and the chromosomal coordinates of each linkage hotspots that have more eQTLs than expected by chance, the number of traits linking to the hotspot (N), the number of those traits that have the over-represented GO attribute (X), the total number of traits that have this attribute (T) and over-represented GO annotation terms are reported.