Table 1 Block Design Example
From: poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
| Number of blocks (B) | Number of compounds per block (n B ) | Number of active compounds expected per block (d B ) | Number of tests needed per block (t B ) | Actual error-rate handled (e) | Actual mixing constraint (m) | Total number of tests needed (t) |
|---|---|---|---|---|---|---|
| 1 | 10000 | 3 | - | - | - | - |
| 25 | 400 | 1 | 492 | 1.02% | 10 | 12300 |
| 50 | 200 | 1 | 92 | 1.09% | 9 | 4600 |
| 77 | 130 | 1 | 52 | 1.92% | 10 | 4004 |
| 91 | 110 | 1 | 44 | 2.27% | 10 | 4004 |
| 100 | 100 | 1 | 44 | 2.27% | 10 | 4400 |
| 500 | 20 | 1 | 20 | 5% | 4 | 10000 |