Figure 1

Mutations predicted to enhance the Fe tetramer SOD characteristics of a5pf69. The mutations are represented in the structure of PDB code 1ids [20], chosen as representative structure of Fe tetramers. Chains A, B, C and D are represented in green, limon, yellow and orange, respectively. The red spheres correspond to iron atoms. The mutations in a5pf69 that are predicted to reinforce the SOD characteristics are in dark grey (Leu7, Leu14, Pro16, His31, Trp77, Ile96, Gly119, Ser120, Trp158, using the 1isa [16] numbering) and those enhancing the tetramer mode are in blue (Ile22, Asn79, Leu164, Gln165, Tyr166). The residues that are discussed in the text are labeled. The figure has been generated using PyMol [21]