Results for the HDAC inhibitor gene signature. The Venn diagram summarizing the findings of significant connections. A represents the instance-level analysis using our new method; B, the set-level analysis using the new method; C, the set-level analysis using the Connectivity Map. The label "AB 13" means that 13 compounds are identified as significant solely by A and B (not C), "B 4" means that 4 compounds are identified as significant solely by B (not A, not C), and so on. The areas are approximately proportional to the numbers they represent.