Figure 3

Number of orthologous probe sets found on Affymetrix array HG-U133 Plus 2.0 for each probe set on Affymetrix array Mouse 430 2.0, using various orthology databases. (A) We mapped all probe sets on array Mouse 430 2.0 (annotation file version 12/19/2005) to their orthologs on HG-U133 Plus 2.0 (annotation file version 11/10/2004), using HomoloGene (version 08/11/2006) and compared with the corresponding orthologous probe sets given by (B) Affymetrix ortholog file 'Mouse430_2_ortholog.csv' (version 07/12/2006) (C) EGO (release 9.0) and (D) Ensembl (as of 08/15/2006). In panels B-D, stacked color bars in each class indicate, for each mouse probe set, if more (red), less (green), the same number (white), or the exact same orthologous probe sets (black) were found as with HomoloGene. The distributions in panels A-D are displayed between 1 and 10. Note that all database versions used in this example are not current versions anymore, EGO in particular having undergone a major rebuild.