Figure 4

Functional analysis of dataset III clusters. Genes in clusters obtained as described in Figure 3 are assessed for motif enrichment in their 5' and 3' flanking regions using FIRE. On the left is the subject of clusters (columns) exhibiting statistically significant enrichment (shades of yellow) or exclusion (shades of blue) of a motif (rows) whose consensus sequence is shown to the right. If known, the name of the motif or the factor that likely binds to it is provided. The clusters are also examined to determine whether the expression pattern of genes in a clustered are associated with a gene segregating in the cross from which the data is derived. The LOD (log of the odds) score of linkage to each 20 Kb bin across the entire yeast genome is shown for a representative subset of the clusters. A potential trans-acting factor encoded within the interval of the elevated LOD score is shown next to the peak.